Turinabol, also known as 4-Chlorodehydromethyltestosterone (CDMT), is an orally active anabolic-androgenic steroid (AAS) that was developed in the 1960s. It is derived from testosterone and has both anabolic (muscle-building) and androgenic (masculinizing) effects.
The primary metabolite of Turinabol is known as 6β-hydroxy-4-chloro-17β-methyl-3, 4-dihydro-2H-1,3-benzoxazin-2-one. This metabolite is formed in the liver through the process of hydroxylation, where an -OH group is added to the 6β position of the molecule. This metabolite is considered a major marker of Turinabol use and can be detected in urine or blood samples through specialized drug testing methods.
Detection of the metabolite allows for the identification of Turinabol use even after the parent compound has been metabolized and cleared from the body. This is significant because Turinabol itself has a relatively short half-life, making it difficult to detect through standard testing methods after a certain period.
It's worth noting that Turinabol is a banned substance in most sports organizations and is classified as a performance-enhancing drug. Athletes who are found to have used Turinabol or its metabolite in competition can face penalties, including disqualification, fines, and suspensions, depending on the governing body and the specific sport's anti-doping regulations.
The detection of this metabolite is crucial for identifying Turinabol use in drug testing. After Turinabol is metabolized in the body, the parent compound is eliminated relatively quickly. However, the metabolite can persist for a longer period, allowing for its detection in urine or blood samples.Turinabol vs Anavar
The metabolite is identified through specialized testing methods, such as gas chromatography-mass spectrometry (GC-MS) or liquid chromatography-mass spectrometry (LC-MS). These techniques can accurately detect and quantify the presence of the metabolite, indicating recent Turinabol use.
Overall, metabolite plays a vital role in identifying Turinabol use in drug testing, enabling anti-doping agencies to enforce regulations and maintain fair competition in sports.
Turinabol, as an oral anabolic steroid, is known to possess some level of hepatotoxicity. It is classified as a 17-alpha-alkylated steroid, which means it has been modified at the 17th carbon position to survive the first pass through the liver. This modification allows Turinabol to be orally active but also puts additional stress on the liver.
The hepatotoxic effects of Turinabol can include liver enzyme elevations, liver damage, and potentially cholestasis (disruption of bile flow). However, the severity and extent of hepatotoxicity can vary among individuals and depend on factors such as dosage, duration of use, and individual susceptibility.
While specific information on the hepatotoxicity of the metabolite is limited, it is reasonable to assume that it may also exert some level of stress on the liver. This is because the metabolite is formed through the metabolic breakdown of Turinabol in the liver.
The cardiovascular effects of Turinabol and its metabolite, are not extensively studied individually. However, based on the general knowledge of anabolic steroids, including Turinabol, it is recognized that they can have potential cardiovascular effects.
The use of anabolic steroids, including Turinabol, has been associated with certain cardiovascular risks. These risks may include:
Increased blood pressure: Anabolic steroids can elevate blood pressure levels, which may put additional strain on the cardiovascular system. High blood pressure is associated with an increased risk of cardiovascular events.
Alteration of lipid profile: Anabolic steroids can negatively impact the lipid profile by reducing levels of high-density lipoprotein (HDL) cholesterol (commonly known as "good" cholesterol) and increasing levels of low-density lipoprotein (LDL) cholesterol (often referred to as "bad" cholesterol). These changes in cholesterol levels can contribute to the development of atherosclerosis and increase the risk of cardiovascular disease.
Cardiac hypertrophy: Prolonged and high-dose use of anabolic steroids can lead to cardiac hypertrophy, which refers to an enlargement of the heart muscle. This condition can disrupt the normal functioning of the heart and increase the risk of cardiovascular complications.
It is important to note that the cardiovascular effects of Turinabol and its metabolite may vary depending on factors such as dosage, duration of use, individual susceptibility, and overall cardiovascular health.
The endocrine system is responsible for regulating hormone production and maintaining hormonal balance in the body. Turinabol and its metabolite, may disrupt the normal functioning of the endocrine system. Turinabol and its metabolite can disrupt the body's hormonal balance in a number of ways, including the following:
Suppression of natural testosterone production: Turinabol, like other anabolic steroids, can suppress the production of testosterone in the body. When exogenous (external) testosterone or its derivatives are introduced, the body's natural production of testosterone may decrease. This can lead to a hormonal imbalance, decreased libido, and potential testicular atrophy.
Estrogenic effects: Turinabol itself has minimal estrogenic activity, but it can be converted into estrogen-like compounds through the process of aromatization. Elevated estrogen levels can lead to gynecomastia (development of breast tissue in males), water retention, and other estrogen-related side effects.
Androgenic effects: Turinabol and its metabolite have androgenic properties, meaning they can promote the development of male characteristics. While androgenic effects are desired for their anabolic effects, they can also lead to side effects such as acne, increased facial or body hair growth, and deepening of the voice in females.
It's important to note that the extent and severity of endocrine disruption can vary depending on individual factors such as dosage, duration of use, and individual sensitivity. Post-cycle therapy (PCT) protocols are often employed after Turinabol use to help restore natural testosterone production and minimize the impact on the endocrine system.
Turinabol, including its metabolite, has been used in the context of bodybuilding and athletic performance enhancement. It is classified as an anabolic steroid, and bodybuilders have used it to promote muscle growth, strength gains, and improve athletic performance. However, it's important to note that the use of Turinabol or any other anabolic steroid for bodybuilding purposes is illegal in many countries and against the rules of most sports organizations.
When used in bodybuilding, Turinabol is typically taken in cycles, where it is used for a specific period of time followed by a break. Dosages used in bodybuilding can vary widely, but it's important to emphasize that the use of anabolic steroids, including Turinabol, carries significant risks to health and can lead to serious side effects. Some potential benefits that bodybuilders may seek with Turinabol include:
Increased muscle mass: Turinabol can promote protein synthesis and nitrogen retention, which may lead to muscle growth and increased muscle mass.
Improved strength: Turinabol is known for its potential to enhance strength gains, which can be advantageous for bodybuilders looking to increase their performance in training and competitions.
Enhanced recovery: Anabolic steroids like Turinabol may help with post-workout recovery by reducing muscle damage and speeding up the recovery process, allowing bodybuilders to train more frequently and intensely.
Despite the potential benefits, it is important to consider the potential risks and side effects associated with Turinabol and its metabolite. These can include liver toxicity, cardiovascular effects, hormonal imbalances, and others. Furthermore, the use of anabolic steroids without proper medical supervision is considered illegal and can result in serious consequences for an individual's health, reputation, and legal status.